r - visualizing clr network in cytoscape -
does know how can proceed generating clr network visualizing network nicely using cystoscape? used minet package generate clr network follows:
source("http://bioconductor.org/bioclite.r") bioclite("minet") library(rgraphviz) library(minet) data(syn.data) mim <- build.mim(syn.data,estimator="spearman") #net<-minet(syn.data,"mrnet","mi.shrink","equalwidth",10) net <- clr( mim, skipdiagonal=1 ) graph <- as(net, "graphnel")
the above code visualizes network in rstudio, have nicer looking network cytoscape can have flexibility of colouring nodes. thanks
you have adjacency matrix in row.names , col names genes. should convert matrix file edge list file:
graph_adj=as.data.frame(as.table(as.matrix(net))) write.table(graph_adj, "graph_adj.txt", sep="\t")
now can open file in excel, edit , import cytoscape.
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